Aloe Extract (Acemannan) – The Wound Hormone


Acemannan is a complex polysaccharide found in the inner leaf gel of the aloe plant. A specialized cell called a leucoplast produces the acemannan. It’s composed of mannose, glucose, and galactose monomers making it into a polysaccharide. Acemannan is the specific component that sets aloe vera apart from the 400 other species of aloe plants. Acemannan contains many nutritional qualities and is mainly responsible for all of the health benefits that aloe vera offers.(1)

Acemannan as “The Wound Hormone”

The Ukrainians are credited with earlier research concerning a “wound hormone” found in certain plant tissues. They observed that this plant hormone accelerated the healing of injured plant surfaces. Using skin lesion models in rats and rabbits they observed that this plant “wound hormone” had the same effect in mammals. Testing was done by injection and by applying on the surface of the skin. This application was much more rapid and complete resulting in a systemic response and faster healing.

Aloe vera with AcemannanImage Source

However, the additional research found that Aloe vera gel was a safe and effective source of the “wound hormone”. This was later identified as Acemannan.(2) It is the Aloe inner leaf gel that is known to stimulate and speed the wound healing processes. However, many aloe-based wound products currently on the market fail to produce the desired effect due to the absence of acemannan.

Benefits and Power of Acemannan

Scientific research has shown that acemannan is useful for a host of issues, including those related to the immune and digestive systems. Below is a list of all the benefits of acemannan:

  1. Helps cells to be more resistant to viruses and pathogenic bacteria.
  2. Improves overall cellular metabolism and functioning.
  3. Promotes healthy inflammation response.
  4. Provides critical lubrication of joints.
  5. Aids in the absorption of water, minerals, and nutrients in the GI tract.
  6. Reduces pain.
  7. Improves vascular flow.
  8. Reduces scarring

Some more benefits are;

  1. Increases the body’s own production of interferon, interleukins
  2. Increase the number of antibody-forming T-cells in the spleen
  3. Increases the number and activity of killer T-cell and increase monocyte activity
  4. Soothes and promotes healing of intestinal disorders. Like; indigestion, heartburn, hyperacidity, peptic and duodenal ulcers, colitis, and haemorrhoids.
  5. Promotes healthy kidney function.
  6. Speeds wound healing.
  7. Reduces allergic reactions.
  8. Stimulates bone marrow activity.
  9. Anti-aging properties.
  10. Supports healthy blood pressure.

How to Consume Acemannan

Now, a sure-fire way to know you are correctly consuming acemannan is to make sure that the aloe vera product you are using is made from the inner aloe vera leaf. As opposed to the outer or whole leaf. There are huge differences between the inner and outer leaf, mainly that certain compounds within the outer leaf can cause gastric distress. You can consume fresh aloe vera directly from the inner leaf, but the taste can be bitter and overpowering. It’s also difficult to consume gel from the inner aloe leaf without also ending up with part of the outer leaf.

We have an amazing dietary supplement in Cellgevity. It combines acemannan with 12 other synergistic organic ingredients to give you a great antioxidant boost for healthy life.

You can share the Aloe vera infographic below with friends –



1 – Aloecure
2 – OAWHealth

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